(Microbial an infection) AMPylation at Tyr-32 and Thr-35 are mediated by bacterial enzymes in the event of infection by H.somnus and V.parahaemolyticus, respectively. AMPylation happens during the effector location and causes inactivation in the GTPase activity by protecting against the interaction with downstream effectors, therefore inhibiting actin assembly in infected cells.
This portion includes any appropriate data that doesn't slot in some other outlined sectionsMore...Miscellaneousi
damaging regulation of protein-containing complex assembly Source: UniProtKBInferred from Actual physical interactioni
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"Molecular cloning and expression of a G25K cDNA, the human homolog of your yeast cell cycle gene CDC42."
This subsection on the 'Construction' portion is utilised to indicate the positions of experimentally decided beta strands within the protein sequence.Additional...Beta strandi
"cDNA clones of human proteins linked to sign transduction sequenced because of the Guthrie cDNA resource Centre ()."
"Identification of a novel protein with GDP dissociation inhibitor exercise for that ras-like proteins CDC42Hs and rac I."
Utilized for info from overview article content where the first experiments are traceable through that article and also for info from textual content books or dictionaries.
The annotation score offers a heuristic measure of your annotation written content of the UniProtKB entry or proteome. This rating can't be utilized as a evaluate of the accuracy on the annotation as we are unable to outline the 'right annotation' for just about any provided protein.Extra...
It ought to be pointed out that although, in concept, two distinct sequences could have a similar checksum value, the likelihood that This is able to transpire is amazingly small.
The annotation score supplies a heuristic evaluate from the annotation information of a UniProtKB entry or proteome. This rating can not be made use of being a explanation evaluate with the accuracy on the annotation as we cannot determine the 'accurate annotation' for any supplied protein.Additional...
"Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42."
UniProtKB Keyword phrases represent a controlled vocabulary that has a hierarchical framework. Search phrases summarise the information of the UniProtKB entry and facilitate the look for proteins of curiosity.More...Keywordsi
"A whole new spouse and children of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell form improvements."